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12.09.2007
Study proves Protexin
02.08.2007
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23.11.2006
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23.11.2006
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23.11.2006
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23.11.2006
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23.11.2006
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Study proves Protexin
A recent study carried out at The University Hospital Surabaya has
found that Protexin can halve the length of time to recovery in cases
of acute diarrhoea in children.
ABSTRACT:
Infection of pathogenic bacterial in diarrhoea will result in the
changes of intestinal micro ecology and the defense mechanism of
intestinal microbe colonisation, in order to overcome the
disadvantaging process, reversal of intestinal flora integrity back to
normal is necessary that could be done by making an improvement to the
normal defense of microorganism colonisation. Imbalance of intestinal
microflora lead to the occurrence of diarrhoea. Manipulation by
combining probiotics and prebiotics (symbiotic) is able to the
improvement of clinical course of acute diarrhoea.
OBJECTIVE:
To manipulate the clinical course of acute diarrhoea in children (the
remission rate and duration of remission) with the administration of
Protexin.
METHODOLOGY:
Children age between 6 months to 2 years suffering from acute
diarrhoea, were alocated for study using experimental design,
randomised double blind placebo control clinical trial. The patients
were randomly assigned into Protexin group and control group.
RESULTS:
25 children in Protexin group and 25 in control group. No differences
in subject characteristic and confounding variables were found in both
groups. At the Protexin group, a more rapid improvement in the
remission rate was significant compared to control group (p = 0.002).
Similar result also was shown in the analysis of fecal form and
frequency of daily fecal excretion where there was a significant
decrease in the symbiotic group. Mean of duration of remission in the
Protexin group was 37 hours in which it was significantly different
when compared to control group of 72 hours.
CONCLUSION:
The administration of Protexin in acute diarrhoea patients can rapidly
improve the remission rate and duration of remission in order to
shorten and prevent further transmission of pathogen. |  
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